Let's explore some more possibilities:
Why not practice grabbing fingers of a practice partner -- reaching in for your legs? It's pretty easy to tweak, wrench, and even lock a finger, once you get a grip on one or more.
Throat punches come to mind, if someone were to grab my head. To be fair, if you practice this, have the attacker grab the head and twist it around, trying to force the good guy to the ground.
This is the way to see if you could punch under pressure.
[Of course, be careful when you practice. No fair trading in your practice partner just because you poked his or her eyes out or landed a solid throat jab.]
Let's not make light of the situation. If an expert grappler gets his 'tree trunks' around you, you're caught.
So, avoid the situation early.
If you see a grappler, head out the door ;-)
If a grappler is running toward you, get someone else (like the police, or security) to stop him early -- for you.
If you are going to have to deal with the turkey yourself, can you prevent the approach? Maybe by throwing something?
If you have nothing to throw, or have decided not to, for legal purposes, can you kick low and hard?
If it's too late, and the grappler is reaching in low, can you slam an elbow down from above?
The above should get you started thinking.
The best way to learn to take on a grappler is to practice against good grapplers.
Most martial artists won't have a chance against a real grappler, until they get in a lot of realistic, rough practice.
Get creative, start practicing, and find a willing grappler to lend a hand ... or two.
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